AH Double Inositol is a dietary supplement in capsules providing two forms of inositol: myo-inositol and d-chiro-inositol.
Inositol in two forms
Inositol, which was once called vitamin B8, is structurally similar to glucose, but its effect on the body is completely different. In nature, it occurs in as many as 9 different stereoisomers. However, one form dominates in supplementation: myo-inositol. The second, less frequently used, but worth attention form is d-chiro-inositol.
Both forms of inositol, myo-inositol and d-chiro-inositol, are very similar, but they show some differences in the way they interact with the human body. Using them together can produce synergistic effects that can produce better results than using each of them alone, as has been noted in many scientific experiments.
One frequently cited study* analyzed the effects of a 40:1 mixture of two inositols, focusing mainly on their role in polycystic ovary syndrome (PCOS) and insulin resistance. PCOS affects up to 10-15% of women of reproductive age, which is why scientists are intensively looking for new tools to fight this condition.
Quoting the authors of the publication:
"DCI (d-chiro-inositol) is involved in mediating the action of insulin mainly on tissues other than the ovary, and MI (myo-inositol) has a specific effect on the ovary"
The authors also indicate that 40:1 is a proportion corresponding to the physiological ratio of these inositols in plasma.
*Monastra G, Unfer V, Harrath AH, Bizzarri M. Combining treatment with myo-inositol and D-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients. Gynecol Endocrinol. 2017;33(1):1-9. doi:10.1080/09513590.2016.1247797
To sum up, AH Double Inositol effectively supplements the diet with inositol. It is supplied in two synergistic forms in a proportion considered physiological.
per 1 capsule | amount | |
---|---|---|
Inositol mix (Myo-inositol, D-chiro-inositol) | 615 mg |
Myo-inositol, capsule shell (hydroxopropyl methylcellulose), rice starch, bulking agent: cellulose; D-chiro-inositol, anti-caking agents: magnesium stearate (plant based), silicon dioxide.
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