Pileje

Permealine 20 bags

• Five ingredients of natural origin
• Documented health-promoting properties
• Prevention of intestinal microbiome dysbiosis
• Support for digestive system function
• Leaky gut syndrome prevention
• Regulation of immune system function
• Cell protection from damage
• Strong antioxidant potential
• Healthy mucous membranes

Permealine is a multicomponent dietary supplement containing substances of natural origin with documented health-promoting properties. Its purpose is versatile support for the health of the digestive system, protecting the organism from the harmful activity of free radicals, and support for the immune system.

This professional preparation contains as many as 5 substances with documented and multi-layered health-improving activity:

- Dietary fibre, including inulin,

- L-glutamine,

- β-carotene,

- zinc,

- green tea leaf extract (Camellia sinensis).

The combination of those five elements allows the supplement to affect the normal functioning of intestinal walls and their mucous membranes in the perfect way. It can be of great significance when it comes to restoring intestinal microbiome balance and preventing the so-called leaky gut syndrome.

The right balance between harmful and positive microorganisms that live in the human digestive system is currently thought to be the core of maintaining the normal functioning of many systems in the organism, especially the digestive and immune systems. Dysfunctions caused by many behaviours and substances that constitute our lives can increase the risk of developing serious diseases and make normal, healthy functioning much more difficult.

Because of abnormal microbiome composition, many toxic substances are formed in the bowel that can damage the walls of the gastrointestinal tract. The condition is one of the main reasons of the leaky gut syndrome, that is “unsealing” between the cells that form intestinal walls. That can lead to increased permeation of various pathogens and allergens to the circulatory system, and, in turn, an (often excessive) immune response of the organism. Some consequences might be food allergies, general inflammation, overproduction of free radicals, and even mental problems, such as depression.

Inulin
Inulin is one of the most tested polysaccharides included in the group of dietary fibres that exhibit prebiotic properties. Prebiotics are compounds that cannot be digested by human enzymes and have the ability to stimulate selectively the growth of beneficial microorganisms inhabiting the bowel. Its positive effect has been confirmed multiple times by clinical tests all over the world.

Positive bacteria are characterised by the ability to digest inulin and transform it into energy essential for their functioning. Thanks to that, they can grow quickly and settle in the right parts of the digestive system. Consequently, they crowd out harmful, often pathogenic, bacterial strains and restore the intestinal microbiome balance.

Apart from eliminating the bacteria that have a negative effect on the human organism, it can bring about a number of other positive effects. Good bacteria have many abilities that stimulate the functioning of the digestive and immune systems. The most important ones are the abilities to regulate intestinal peristalsis, regenerate large intestine wall cells, regulate the immune response, and prevent the recolonisation of the bowel by pathogenic microorganisms.

L-glutamine
Glutamine is a relatively exogenous amino acid that occurs in the organism naturally. It means that in some situations, its concentration may drop and it is necessary to deliver it from the outside in the form of food or supplements.

There are many scientific reports confirming the efficiency of supplementing it in the case of various diseases of the digestive system, for example, in the leaky gut syndrome. Glutamine is one of the main elements of intestinal walls, so its increased supply can stimulate their regeneration and increase the secretion of the natural protective barrier, that is mucus.

Additionally, it is suggested that it can be applicable in regulating the immune response and supporting the organism’s immunity. Scientists say that it can inhibit excessive inflammation within the digestive system, which can bring relief in the irritable bowel syndrome or inflammatory bowel diseases. Apart from that, its support in sealing and improving the functioning of mucous membranes enhances immunity to frequent bacterial and viral infections.

β-Carotene (vitamin A)
Referred to as a carotenoid, the compound is a powerful antioxidant that can be found naturally in many plants. In the human organism, it can be converted to another compound of crucial significance for health – vitamin A.

β-Carotene is valued particularly for its extraordinary ability to intercept free radicals of many kinds. It has been demonstrated that it is more efficient in removing singlet oxygen (one of the most dangerous radicals) than vitamins C and E. Eliminating the harmful molecules from the organism is essential for protecting many cells from damage. It can also prevent DNA mutations, which are the basic factor of cancer development.

The carotenoid can also exert a direct effect on the health of the digestive system. Specialists have noticed that β-carotene supplementation helps to increase mucus secretion in the bowel, which improves their functioning and prevents frequent infections that can be one of the factors of developing the leaky gut syndrome.

Zinc
Zinc is an element that participates in many aspects of human health, from the normal development and growth, regulating the immune response, supporting learning processes, to the mechanisms of DNA repair and its protection from damage.

Indirectly, it also serves as an antioxidant. It is a crucial component of a very powerful antioxidant that occurs in the organism naturally – superoxide dismutase, which is responsible for neutralising the superoxide radical.

Zinc is also relevant for the development and functioning of the immune system. That is because it affects changes in the profile of produced cytokines by, for example, inhibiting the synthesis of pro-inflammatory factors. That can prove very significant in diseases connected with the oversensitivity of the system or digestive system inflammations.

Green tea extract
Green tea is a beverage that was appreciated as early as in antiquity, both thanks to its taste and health-promoting properties. Extracts of the plant are extremely rich in polyphenol compounds, which are the most powerful antioxidants we know of. Their properties are significant for protecting many cells and structures (including the DNA) from damage and delaying aging processes in the organism.

To sum up, Permealine is a professional dietary supplement containing fully natural components with powerful health-promoting properties. Its purpose is the protection and regeneration of the digestive system, the regulation of the immune system, and supporting the organism in the fight against free radicals. It is particularly recommended for people who want to restore their intestinal microbiome balance and prevent the consequences of the leaky gut syndrome.