Swanson

L-Methionine 60 caps.

• Patented method of production AjiPure®
• Pharmaceutically pure amino acid
• Improves memory and cognitive functions
• Positively influences well-being
• Supports methylation processes
• Decreases the level of homocysteine
• Decreases depression symptoms
• Hepatoprotective properties
• Antioxidant properties
• Neuroprotective effect
• The increase of glutathione
• Increased concentration
• Detoxification of the organism
• Support of liver work
• Appropriate for vegans

Swanson L-Methionine is a dietary supplement providing 500 mg of L-methionine amino acid in one portion. The preparation was created in cooperation with a Japanese company Ajinomoto, which produces amino acids with pharmaceutical quality.

L-methionine is an exogenous amino acid containing in its molecule a sulfur atom. Exogenous amino acids need to be provided to the organism from outside, as the organism does not have the enzymatic systems that would enable their synthesis. L-methionine constitutes a substrate for the synthesis of many active substances taking part in many important metabolic processes. Optimal efficiency of these processes is essential to maintain proper functioning of the organism.

L-methionine becomes converted in the organism to S-adenosyl L-methionine (SAMe), as a result of transporting adenosyl group ATP on the molecule of methionine. This process is catalyzed by the enzyme called methionine adenyltransferase. SAMe is a biologically active form of methionine, functioning as a universal donor of methyl groups in the organism. It takes part in many reactions of transmethylation, for which substrates are proteins, nucleic acids and phospholipids.

Methylation dependent on SAMe conditions the synthesis of phosphatidylcholine, a compound essential to maintain the structure and functions of cell membranes. It constitutes the source of choline, which is a precursor for the key transmitter in the nervous system – acetylcholine, which has massive influence on the processes of memorization and mood. Choline is also essential to create myelin sheaths, which ensure optimal pace of transmitting nerve impulses and protect neurons, which positively influence intellectual abilities and cognitive functions.

There are some reports on antidepressant properties of SAMe. It is related to increasing the amount of serotonin in the brain by SAMe (which constitutes the mechanism of activity of tricyclic antidepressants). One of the theories of developing depression are metabolism disorders of one of carbons related to transmethylation in the processes of neurotransmitter synthesis. Control research shows that SAMe is more effective in the treatment of depression than placebo and comparable to the effect of tricyclic antidepressants (TCAs).

L-methionine is used for the synthesis of glutathione. Glutathione is a tripeptide which constitutes an incredibly important antioxidant system of the organism. It appears most abundantly in the liver, where it enables the elimination of the harmful substances. It is coupled with xenobiotics (unfamiliar substances to the organism), i.a. with free radicals, inactivating them, making them harmless to the organism. Glutathione deficiency results in non-complete metabolism of these foreign substances, the example of which is the reaction with the active, hepatotoxic metabolite of paracetamol – N-acetyl-p-benzoquinone imine (NAPQI). Insufficient amount of glutathione causes that NAPQI is not completely bound, which leads to liver necrosis.

To sum up, Swanson L-Methionine is a high-quality dietary supplement. It positively influences the comfort of life. It is especially recommended to people with depression, bad mood and mood fluctuations, in order to support liver, improve memory and intellectual abilities and also as prophylaxis.