Leaf of common rue (Folium Ruta), contains many active substances: alkaloids (rutamine, arborinine), flavonoids (rutin), Furanocoumarin (rutamarin), essential oils (limonene, pinene). Preparations from the leaves of common rue are diuretic and cholagogic, seal blood vessels and increase their flexibility. Touching of fresh leaves is not recommended by allergy sufferers, because of possible allergies.